Preheat the oven to 325°F (170°C) and adjust an oven rack to the middle position.
Butter and flour a 12-cup (2.8-l) non-stick Bundt pan, making sure to get into all the crevices. Then turn the pan upside down over the sink and tap to remove any excess flour.
In a large bowl, whisk together the flour, salt, baking powder, baking soda, nutmeg, cinnamon, cloves, and ginger.
In the bowl of an electric mixer fitted with the paddle attachment or beaters, beat the butter and granulated sugar on medium speed until just blended. It will be a little crumbly.
Add the eggs, 1 at a time, beating well after each addition and scraping down the sides of the bowl as necessary. Continue beating on medium speed until very light and creamy, about 3 minutes.
Beat in the pumpkin, scraping down the sides as necessary. The mixture will look grainy and curdled. Don't worry. It's okay.
Reduce the speed to low and gradually add the flour mixture, mixing until just combined, about 1 minute. Scrape down the sides and bottom of the bowl and mix just until the batter is evenly combined.
Scrape the batter into the prepared pan and smooth the top with a rubber spatula. Bake until a toothpick or cake tester inserted in the center comes out clean, 70 to 90 minutes.
Let the pumpkin pound cake cool in the pan on a wire rack for 10 minutes. Then turn the pan upside down onto the rack, carefully remove the pan, and let the cake cool completely.